The context
Where the work begins
Bacteria can grow in the tiny gap between a tooth and its filling, causing infection and damaging the restoration. During graduate research at U of T, Cameron Stewart formed porous silica particles around an antimicrobial so it could be released slowly near a filling. That work became the basis of Mesosil.
The takeaway
What follows
The company secured FDA 510(k) clearance by supplying its technology to established dental companies rather than selling directly to dentists. Mesosil raised $2.3 million in 2024 and maintains research ties with U of T. Stewart is now considering how to increase production, potentially through a small chemical manufacturing facility, while exploring other applications.
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